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          _____ his knowledge of the mountainous country, John Smith was appointed as our guide.
            
           A. In spite of      B. On account of   C. Regardless of   D. In place of
          			
          


			
          

		
          
		
		
	
          
		
          
			
          
				
          
				
          B
             
          解析:
               
          On account of(=because of)由于，因?yàn)�。regardless of(=without worrying about)不顧；
          				
          
							
          
			
          
			
          
			
			
          
		
          
	
          

		
          

		





			
          
		
          
		
				
          
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